GONORRHOEA – MANAGEMENT 2

Uncomplicated genital, anal or pharyngeal infections

Single dose regimens cure most cases of uncomplicated gonorrhoea. Treatment for chlamydia may also be given particularly if local experience is that postgonococcal urethritis is common. Sexual abstinence is of benefit during therapy. Admission to hospital is usually indicated for children with gonorrhoea. Pharyngeal infections are less responsive to treatment than genital infections.

Penicillin susceptible infection (first line treatment where PPNG is uncommon)

Adults:

Amoxycillin 3 g given with 1 g probenecid as a single oral dose for anogenital infections and as a daily dose for 3 days for oropharyngeal infection or Aqueous procaine penicillin G 3 g intramuscularly (1.5 g at 2 sites) with probenecid 1 g orally as a single dose.

Children:

Amoxycillin 50 mg/kg given with probenecid 25 mg/kg as a single oral dose or Aqueous procaine penicillin G 100,000 units/kg intramuscularly with probenecid 25 mg/kg orally as a single dose.

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